It’s important to discuss your use of aspirin with your doctor, as you may have factors that increase your risk of overdose. In older adults or people with malfunctioning kidneys taking regular medium to high-dose aspirin (325-650mg every 4 to 6 hours), dehydration or hot weather can heighten the risk of chronic overdose.
A dose of 500 milligrams per kilogram of body weight (34,000mg for a 68kg person) is considered a potentially lethal dose of aspirin, and could result in death. An acute aspirin overdose may be accidental or intentional.Ī toxic dose of aspirin for a human adult is considered to be 200 to 300 milligrams per kilogram of body weight (works out to be 13,600 to 20,400mg of aspirin for a person who weighs 68 kg ). An aspirin overdose can occur after a single large dose (this is called an acute overdose) or develop gradually after taking lower doses for a long time (this is called a chronic overdose).
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